Intussusceptive Angiogenesis: A Biologically Relevant Form of Angiogenesis
نویسندگان
چکیده
منابع مشابه
Intussusceptive angiogenesis: a biologically relevant form of angiogenesis.
Angiogenesis, i.e. the development and growth of blood vessels, is a major topic of research as it plays an important role in normal development and in various pathologies. Recent evidence revealed the existence of different mechanisms of blood vessel growth, including sprouting and intussusceptive angiogenesis, vascular mimicry, and blood vessel cooption. The latter two have only been observed...
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Angiogenesis is defined as the growth and development of new capillary blood vessels from pre-existing vasculature [1]. It is requisite in metazoans because the transfer of nutrients and wastes has to be accomplished by diffusion through the tissue and hence, the respiring cells need to be within 100–200 μm of the blood vessels, which is the diffusion limit for oxygen [2]. Angiogenesis is a nor...
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Angiogenesis, the growth of vascular structures, is a complex biological process which has long puzzled scientists. Better physiological understanding of this phenomenon could result in many useful medical applications such as the development of new methods for cancer therapy. We report on the development of a simple computational model of micro-vascular structure formation in intussusceptive a...
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Angiogenesis or formation of new blood vessels from preexisting vasculature is a key process in some physiological conditions such as wound healing, growth, and action of female reproductive organs. Moreover, disturbance of the mechanisms of physiological angiogenesis has a role in pathogenesis of some diseases in the form of overproliferation of blood vessels such as cancers, psoriasis, arthri...
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Angiogenesis is a highly coordinated, extremely complex process orchestrated by multiple signaling molecules and blood flow conditions. While sprouting mode of angiogenesis is very well investigated, the molecular mechanisms underlying intussusception, the second mode of angiogenesis, remain largely unclear. In the current study two molecules involved in vascular growth and differentiation, nam...
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ژورنال
عنوان ژورنال: Journal of Vascular Research
سال: 2012
ISSN: 1018-1172,1423-0135
DOI: 10.1159/000338278